Definitions for: Setback

[n] an unfortunate happening that hinders of impedes; something that is thwarting or frustrating

Webster (1913) Definition: Set"back`, n.
1. (Arch.) Offset, n., 4.

2. A backset; a countercurrent; an eddy. [U. S.]

3. A backset; a check; a repulse; a reverse; a relapse.
[Colloq. U.S.]

Synonyms: blow, reversal, reverse

See Also: happening, natural event, occurrence, whammy